CLINICAL REPORT Microcephaly, Intellectual Impairment, Bilateral Vesicoureteral Reflux, Distichiasis, and Glomuvenous Malformations AssociatedWith a 16q24.3 Contiguous Gene Deletion and a Glomulin Mutation

Microcephaly, Intellectual Impairment, Bilateral Vesicoureteral Reflux, Distichiasis, and Glomuvenous Malformations AssociatedWith a 16q24.3 Contiguous Gene Deletion and a Glomulin Mutation Matthew G. Butler,* Susan L. Dagenais, Jose L. Garcia-Perez, Pascal Brouillard, Miikka Vikkula, Peter Strouse, Jeffrey W. Innis, and Thomas W. Glover Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan Department of Human DNA Variability, GENYO (Pfizer-University of Granada-Andalusian Government Center for Genomics and Oncological Research), Granada, Spain Department of Radiology, University of Michigan Medical School, Ann Arbor, Michigan Laboratory of Human Molecular Genetics, de Duve Institute, Universit e Catholique de Louvain, Brussels, Belgium